For REI fellows · 2027 cycle
Reticular Fellows Research Grant
Euploid means the right number of chromosomes. It says nothing about the single genes on them.
Single-gene causes of euploid loss are the next frontier of reproductive genetics. This grant funds one REI fellow to study them in failed euploid transfers and losses: $10,000 to your institution, plus optional genomic sequencing and bioinformatics for up to 50 cases.
- Applications open
- Oct 26, 2026at ASRM 2026
- Application deadline
- Dec 1, 202611:59 PM ET
- Recipient announced
- Dec 15, 2026one award
A euploid result · illustrative
Chromosomes counted. Genes not reported.
Illustration. A PGT-A copy-number plot shows two copies of each of chromosomes 1 to 22, marked euploid. Zooming into one chromosome shows a gene and a stretch of its DNA with one changed letter, which the euploid result does not report.
PGT‑A · copy number
EuploidOne gene’s sequence
Not in the resultMeet us at ASRM 2026
The Single-Gene Side of Euploid Loss
Monday, October 26 · 6–9 PM EDT Pratt Street Ale House, across the street from the Convention Center. Applications open that night.
Why it matters.
~1 in 2
couples with recurrent loss finish the parental workup with no cause.
~1 in 4
families with unexplained, recurrent euploid loss had a possible single-gene cause.
Sources: Kutteh et al., Reprod Biomed Online 2024; Aminbeidokhti et al., medRxiv 2025 (preprint).
Maya and Daniel
An illustrative couple
Two IVF cycles. Seven embryos, four euploid by PGT-A.
Three euploid transfers. One negative test. Two losses at 7–8 weeks.
Complete workup: normal.
What did we miss?
Example research questions.
You bring the clinical question. Our partner CLIA lab handles the sequencing and our team the bioinformatics.
How often could one gene explain repeated euploid failure?
Are single-gene findings as common when transfers succeed?
Do parents' genomes explain failures that the standard workup misses?
Which failure pattern points to a single-gene cause?
Does expanded genome analysis change what REIs and couples do and which embryos are prioritized?
The award
Funding, genomics and bioinformatics, and first authorship.
$10,000
To your institution
For project costs such as participant expenses, biostatistics, genetic counseling, sample collection and shipping, analysis software, and IRB fees. Up to $1,200 may cover travel to present the findings; not for salary, equipment, or clinical care.
50 cases
Optional · in kind
Whole-genome sequencing of the adults in each case by our partner CLIA laboratory, plus an initial bioinformatic analysis from our team that can draw on the embryos' existing raw PGT-A data. You choose the cases.
First author
Fellow first, PI last
Your faculty mentor, as principal investigator, is last author. Reticular scientists who contribute the genomic analysis and meet ICMJE criteria are co-authors.
Timeline.
Oct 26, 2026
Applications open
Announced at our ASRM happy hour. Optional 1:1 information calls through December 1.
Dec 1, 2026
Applications due
11:59 PM ET.
Dec 15, 2026
Recipient announced
One award.
Jan–Feb 2027
Agreements and IRB
Research and data-use agreements, and your local IRB.
Mar 2027–Jun 2028
The study
Consent where needed, samples, sequencing, analysis.
2027–28
Present your work
Interim or final results as an abstract, poster, or talk at ASRM, ASHG, SRI, or PCRS.
How to apply
One PDF, one email.
Who can apply
- REI fellows at any training year in an ACGME-accredited program. Applications are screened on timeline: protected research time, when your training ends, and expected IRB approval.
- A faculty mentor who will serve as PI of record.
- Selection and the award do not depend on whether you, your mentor, or your program order Reticular's clinical tests, now or later.
Your application, in this order
Cover sheet
Page 2 of the downloadable PDF.
Proposal, up to 4 pages
Problem statement, background, aims, methods (which cases, what samples and data you already have, and what you want sequenced), and a timeline to the meeting you would present at.
CV or NIH biosketch
Up to 2 pages — whichever you already have.
Mentor letter, up to 1 page
Confirming your mentor will serve as PI of record and support your time on the project.
One PDF · Arial 11 pt · margins ≥ 0.5 in
Send it
Email one PDF to christina@reticular.com by 11:59 PM ET, December 1, 2026.
Subject line: Fellows Research Grant — [Your Full Name]
Review
How applications are scored.
Applications are reviewed by our clinical and scientific advisors, including Sara Vaughn, MD, former medical director of Spring Fertility Silicon Valley.
Significance
Does the question matter to patients, and could the answer inform counseling or care?
25
Approach
Can the design answer the question with genomic data — our analysis or your own — and is the analysis plan set in advance?
30
Feasibility
Can you finish this in about 12 to 18 months, given your cases, samples, and training timeline?
25
Environment
Mentorship, access to cases and samples, statistical support, institutional capacity to execute.
20
Reviewers step aside from any proposal from an institution they are affiliated with.
Common questions
Quick answers.
One patient, couple, embryo cohort, or pregnancy loss. Sequencing covers the adults; for embryos, the analysis uses existing raw PGT-A data, not new samples. The 50 includes any control cases. Sample details are confirmed on award.
Yes — using it counts toward your score under Approach, unless your cases already have exome or genome data. Say on the cover sheet whether you will use it.
Yes. List any other funding you hold or have applied for on the cover sheet.
Contact
Ask before you apply.
Book a 30-minute call to talk through your idea, or email us any question.